Expresión de búsqueda: STAT5 TRANSCRIPTION FACTOR 
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Descriptor Inglés:   STAT5 Transcription Factor 
Descriptor Español:   Factor de Transcripción STAT5 
Descriptor Portugués:   Fator de Transcrição STAT5 
Categoría:   D12.644.360.024.342.500
D12.776.157.057.186.500
D12.776.476.024.421.500
D12.776.930.840.500
Definición Inglés:   A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA. 
Nota Histórica Inglés:   2006(1992) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   50798 
Identificador Único:   D050799 

Ocurrencia en la BVS:
 

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